QSAR Modeling, Docking and Insilico ADMET Studies of Lanosterol Synthase Inhibitors
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چکیده
منابع مشابه
QSAR Modeling, Docking and Insilico ADMET Studies of Lanosterol Synthase Inhibitors
Lanosterol Synthase is an attractive target for antihypercholesterolemeic drug design. A set of 26 molecules having lanosterol synthase inhibitory activity was used for pharmacophoric hypothesis and atom based QSAR analysis. Inhibitory concentrations (pIC50) of these compounds were ranged from 7.452 to 8.721. Pharmacophoric hypothesis AAHPR.174 had the best survival score of 3.560. On the basis...
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ژورنال
عنوان ژورنال: Oriental Journal of Chemistry
سال: 2017
ISSN: 0970-020X,2231-5039
DOI: 10.13005/ojc/330428